What does the prefix Rube mean?

Answer 1

The prefix 'rubi', and its variants are shortend forms of 'rubicund,' Latin for 'ruddy' or reddish coloured, referring originally to the reddish colour of the Rubicon river.

The noun 'rube' is a classic allusion, equivalent to the current 'redneck'.

Answer 2

The prefix "rube" generally means a naive or unsophisticated person, often used in a derogatory way to describe someone who is easily deceived or gullible.