Many. In fact there are ten of thousands of instrument rated pilots in the world and growing steadily. In the time it took me to write this answer, more than 15 individuals qualified as an instrument rated pilot.
They do there are many pilots in the world to do the flights
You will need 2 pilots
In 2010 there were 21,063 civil aircraft registered, and about 28,000 Private Pilots, and 10,000 certified glider pilots.
About 20,000 American spitfire pilots died in WW2.
Pilots will reference many instruments throughout their flight. Attitude indicators, speed, altimeters, vertical speed indicators, turn indicators, navigation displays, flight management systems and many engine instruments that display temperature, rpm, various pressures such as oil, manifold and hydraulic. The most important instrument is probably their fuel gauge.
There is no exact data as to how many airline pilots are in the world. There are an estimated 800,000 in the United States.
544 allied pilots and i don't know the stats for Luftwaffe
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There are two ace Knightmare pilots in the Code Geass.
There are quit a few pilots in the US Army, of course most of which are helicopter pilots, if I had to put a number on it I would say approximately 10,000
lots