Well, by just simply ignoring it at moving farther west. This was one of the many things that caused the revolutionary war.
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proclamation of 1763
The Royal Proclamation of 1763 was issued by King George III. It was an order prohibiting the colonists from settling past a boundary line along the Appalachian Mountains.
stopped the americans from moving west of the appalachian mountains.The proclamation of 1763 kept colonists out of Native American lands west of the Appalachian mountains. It also kept colonists out of the Fur trade.Cancelled all previouse land grants given to the colonies by past kings and parliments
The Proclamation Line,1763
After the Proclamation of 1763, the colonists in America were not allowed to cross territory west of the Appalachian Mountains.