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If your doctor has prescribed morphine for you tell them that you take Benadryl. USUALLY it is okay to combine them as Morphine can cause you to feel itchy. Both Benadryl and Morphine can cause drowsiness so caution should be used always when combining medication together. The maximum dose of Benadryl for an adult is 50 mg every 6 hours. It is difficult to answer this question as there are different kinds of Morphine, specifically MSIR which is short acting morphine and Extended Release or "ER Morphine (such as MS Contin) with is time released. DO NOT BREAK OR CHEW ER MORPHINE as it will "dump" it's entire amount into the body at one time instead of being given over a 8 to 12 hour period. (Avinza is a 24 hour morphine pill, extreme caution should be used when dealing with ER Morphine as it is available in generic and numerous difference brand names, the most common being Avinza, Kadian and MS Contin.) IF you have been taking morphine for a period of time, at least several months and are not sedated by it then you probably could take Benadryl and Morphine together. Better advice is "When in doubt call your doctor or your pharmacist!" Overdosing on medication is easier than one thinks, it is much better to be safe than sorry.

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15y ago
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13y ago

No, because I just googled if it was safe to mix the two and have been alive for the past 5 hours and it's still looking good. but from what i've read, it's not recommended ;)

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13y ago

i just did

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Q: Will taking morphine and benadryl together kill you?
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