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An empty stomach, with generally less acid than a stomach with food in it, will have a HIGHER pH. Acid is below 7 pH and base is above 7 pH. An empty stomach has less acid. If a medication is to be taken on am empty stomach, the goal is to have the pill survive past the stomach without reacting with stomach acid. These medications are better when absorbed in the duodenum or small intestine. Venous blood flow from the intestines first passes through the liver, which is necessary for some medications to become activated. If these medications are broken down and absorbed to the bloodstream through the stomach, then they do not get this early "first pass" through the liver to become activated, and you lose much of the medication's benefit.

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10y ago
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14y ago

Because of acidic adversity in the stomach

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12y ago

for better absorption

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Q: Why take penicillin on an empty stomach?
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Related questions

What happens if you take a penicillin pill with a empty stomach?

You're suppose to take it on an empty-stomach. Or 1 hour before a meal or three hours after.


How soon can I eat after taking penicillin?

If the Penicillin says to take on an empty stomach, take an hour before eating, or two hours after. Some penicillins can be taken with meals. Just read the label.


What happens if you take penicillin on a full stomach?

the penicillin would be deactiviated and therefore not work as the acid in your stomach gets higher to digest the food the penicillin will not perform how it should do !! =D


Should colostrum be taken on an empty stomach or can it be taken with juice or food?

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It burns and feels like indigestion when taken on an empty stomach. I take it with meals and plenty of water


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I would not recommend that you take Zyrtec on an empty stomach because it can give you a upset stomach and diarrhea as well. It can also make you feel really bad too.


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Some penicillins, notably penicillin V, should be taken on an empty stomach, but others may be taken with food. Check package directions or ask the physician or pharmacist for instructions.


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