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1. Probenecid inhibits the tubular secretion of penicillin thus increasing the serum concentration of penicillin.

2. Lesser dose of Penicillin is needed

3. Therefore, there will be less side effects of penicillin.

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Q: Why is probenecid given with a penicillin?
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Related questions

Are there any warnings with penicillin?

There may be an interaction between penicillin and some compounds: birth control pills containing estrogen, chloramphenicol, tetracycline antibiotics, methotrexate, probenecid, colestipol, warfarin... hypersensitivity (anaphylactic) reactions can occur in individuals with a history of penicillin hypersensitivity ... Incompletely developed renal function in newborns may delay elimination of penicillin.


When should penicillin be given to horses?

A horse should be given penicillin when a veterinarian determines the horse has a bacterial infection that will respond to the penicillin.


Can penicillin be uses on boils?

Yes, penicillin can cure boils. The penicillin usually given for boils is Flucloxacillin. If a person is allergic to penicillin, they will be given a different antibiotic.


Did penicillin help in the trenches?

If you are talking about WWI trenches, given that penicillin was discovered in 1938, no, it did not help


Can you give penicillin in the muscle?

Yes, most injectable penicillin formulations are designed to be given intramuscular.


What happened to the mice that were not given penicillin?

they died


What nickname was given to penicillin?

The miracle drug


What is the amount of penicillin given in a shot?

Penicillin has very large margin of safety. Usual adult dose of procaine penicillin is 600,000 I.U. (International units) per day. The adult dose of penicillin can be given up to 24 million I. U. of crystalline penicillin per day in meningitis. The first dose of penicillin, that was given to the patient as trial dose was only 5000 I.U. few times per day. It was given during second world war. The most wonderful thing that this small dose did work. The patient started to improve. Later on died of infection, only because the stock of penicillin got exhausted.


Should penicillin be given in muscle or under the skin to cattle?

It should be given in the muscle.


How often should penicillin be given to a goat?

Only occassional


Can penicillin causes anaphylactic reactions?

which antibiotics can be safely given


How does penicillin?

Penicillin works by inactivating an enzyme necessary for the cross linking bacterial cell walls.Its given to people who use it and get cured