Penicillin is rarely used now a days. It is because it can cause anaphylactic reaction in few patients. Patient can die instantly out of this reaction. Even a test dose can lead to the death of the patient. Patient becomes unconscious in seconds. Patient gets severe spasm of the tracheobronchial tree and the blood pressure falls down. Pulse may not be felt at all. Nobody will like to take the risk of anaphylactic reaction of the penicillin. Never the less penicillin is still the life saving drug.
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