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During extrusion, the damp mass of powdered material is past through a screen leading to the formation of strip-like granules. These granules are then fed onto a revolving plate where they are broken down into smaller lengths. A spherical form is produced due to the plastic nature of the material.
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What are the methods of granulation?
There are two types of granulation they are Wet Granulation and Dry Granulation.Wet granulation and dry granulation depends on the type of fertilizer granulators and whether adding water during granulation.In general, Roll Extrusion Granulator(Azeus Fertilizer Machinery) is dry granulation machine. It requires moisture of raw materials less than 40% and no water added during granulation. So, it's compound fertilizer granules are also dry, in long-stick shape.But, as for New-type Granulator(organic fertilizer by Azeus Fertilizer Machinery) and Pan Granulator (both organic and compound fertilizer), with required a low moisture of raw materials, water must be add during granulation. Or, the fertilizer granulation will fail.
What is the difference between dry granulation and wet granulation?
Wet meaning you wet the ground first with a hose
What are the disadvantages of wet granulation?
As wet granulation requires multiple steps for extra blending, granulation, and drying, it can be time-consuming. Wet granulation is also unsuitable for water sensitive active pharmaceutical ingredients due to their incompatibilities with water. As the granule are dried in elevated temperatures, the high temperatures may lead to instability. Failure to accurately determine the endpoint of the wet granulation process may also lead to compaction and dissolution problems. The material may also stick to the walls of the machine during the process instead of being added to the granules.
What is wet granulation used for in the pharmaceutical industry?
Wet granulation is used to improve the flowability of the particles, increase the uniformity of the contents of the drug, unify the size of the particles, reduce the segregation of different components of the drug, and to increase the density of the material. Due to the advantages of wet granulation, it is the most common granulation method in the pharmaceutical industry.
What are the advantages of roller compaction over wet granulation?
Roller compaction can continuously produce tablets whereas wet granulation produces tablets in batches. Roller compaction is also simpler with fewer steps and it requires less equipment and floor space. As roller compaction requires less time and energy, it is less expensive than wet granulation.
What type of weather occurs during a monsoon?
During a monsoon, heavy rainfall occurs due to the seasonal shift in wind patterns. This can result in prolonged periods of intense rainfall, leading to flooding and landslides in some regions. Monsoons are characterized by a distinct wet season followed by a dry season.
What happens at the jaculation?
Ejaculation occurs with a sexual climax during sex or masturbation or during so called "wet dreams"
Where and when do hurricanes?
hurricane occurs in wet seasons hurricane occurs in hot wet climates
When and where hurricane occur?
hurricane occurs in wet seasons hurricane occurs in hot wet climates
What is the difference between wet granulation and dry granulation?
The dry granulation process is used to form granules without using a liquid solution because the product to be granulated may be sensitive to moisture and heatWet granulation involves the massing of a mix of dry primary powder particles using a granulating fluid (the process of adding a liquid solution to powders). The fluid contains a solvent which must be volatile so that it can be removed by drying, and be non-toxic
Is Antarctica wet area?
No. Antarctica is frozen, with some melting and re-freezing that occurs during summer periods.
What time of the year that wet season occurs?
Sometimes wet season occurs in March or even in May due to spring.
