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The active ingredient in both pills is the same (Cetirizine). The difference between hydrochloride and dihydrochloride is the difference between the non active ingredients in the pills that are added to the drug so that there is enough bulk to make a pill. The above 'advice' is simply rubbish. Any (old Skool) A-Level chemistry student knows the difference between 'hydrochloride' and 'di-hydrochloride': Not the same molecule.However, in layman's terms: cetirizine di-hydrochloride is the real thing and is less likely to make you drowsy. Cetirizine hydrochloride is a copycat molecule to work around patent laws.From personal experience, cetirizine hydrochloride makes me drowsy, whereas cetirizine di-hydrochloride does not. :-)

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15y ago
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Ian Cockayne

Lvl 1
2y ago
Question: apparently the dihydrochloride has added lactose, will this affect people with lactose intolerance?
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13y ago

Diphenhydramine citrate gets quicker into your bloodstream than diphenhydramine hci. Citrate is used in advil people, while hci is used in benadryl

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Q: What is the difference between Cetirizine hydrochloride and Cetirizine dihydrochloride?
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Can you drink alcohol with Levocetirizine dihydrochloride?

Nothing... I take cetirizine hydrochloride myself - prescribed to alleviate hay fever. To quote the information leaflet from the box the tablets came in... "No significant interactions have been observed between alcohol and cetirizine at the recommended doses. "


What is the difference between avil and cetirizine?

The active ingredient in Cetirizine is Cetirizine hydrochloride. The active ingredient in Avil is pheniramine maleate. Both are used to treat symptoms of allergies. You should ask your pharmacist to confirm this information.


What is the difference between cetirizine and hydroxyzine?

Cetirizine is a second-generation antihistamine commonly used to treat allergies, while hydroxyzine is a first-generation antihistamine with sedating properties that is used for anxiety and itching. Cetirizine is less likely to cause sedation compared to hydroxyzine.


What is the difference between Betahistine dihydrochloride and Betahistine mesylate?

Betahistine dihydrochloride and betahistine mesylate are both forms of betahistine, a medication used to treat vertigo and Meniere's disease. The main difference between them is the salt form in which the betahistine is administered - dihydrochloride or mesylate. Both forms are effective in treating vestibular disorders, but some patients may respond better to one form over the other due to individual differences in drug metabolism.


What is the difference between Betahistine hydrochloride and Betahistine dihydrochloride?

Betahistine hydrochloride and Betahistine dihydrochloride are salt forms of the same drug, betahistine. The difference lies in the chemical composition of the salts, with hydrochloride containing one hydrochloride ion per molecule and dihydrochloride containing two hydrochloride ions per molecule. Both forms are used to treat vertigo and Meniere's disease.


What is the difference between acetyl l carnitine hydrochloride and acetyl l carnitine?

Acetyl L-carnitine and acetyl L-carnitine hydrochloride are two forms of the same compound. The only difference lies in the type of salt they are combined with. Acetyl L-carnitine hydrochloride is the hydrochloride salt form of acetyl L-carnitine.


What is the difference between Amantadine and Amantadine hydrochloride?

Actually they are the same substance. A chloride ion is introduced to amantadine to become amantadine hydrochloride. This will be helpful to increase the solubility of amantadine. Most drugs are absorbed faster by the body if they are salts, especially hydrochloride salts and sulfate salts


What is the difference between benzocaine and benzocaine hydrochloride?

Benzocaine is a local anesthetic used to numb skin and mucous membrane. Benzocaine hydrochloride is the hydrochloride salt form of benzocaine, which is more water-soluble than benzocaine and may have different pharmacokinetic properties. Benzocaine hydrochloride is often used in pharmaceutical formulations that require water solubility.


Can you take Zyrtec with phentermine?

There are no known interactions between Zyrtec (cetirizine) and phentermine.


IS there a difference between Oxycontin hcl 5mg and oxycodone ir 5mg?

Yes Oxycontin hydrochloride is a time released tablet and oxycodone ir is an instant release tablet.


Can you take cetirizine while on antibiotics?

There are no interactions between any antibiotics that I can think of and cetirizine however there are many types of antibiotics out there so something specific would give a better certainty to any answer you'll receive.


Is pyridoxine hydrochloride ionic or covalent?

Pyridoxine hydrochloride is an ionic compound. Pyridoxine is a vitamin B6 derivative, which acts as the cation and hydrochloride serves as the anion, resulting in an ionic bond between them.