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The first person who answered this question is an idiot. Grapefruit juice contains CYP3A4 inhibiting compound so yes, it does interact with various drugs, xanax being one of them. 3YP3A4 is the enzyme which metabolises xanax so drinking grapefruit juice with xanax potentiates the xanax because less of the xanax gets converted into inactive metabolites. Its not dangerous to take xanax with grapefruit juice at all, it just makes the xanax a little stronger so the obvious way to counteract that is to take less xanax. Heres a list of drugs that are metabolised by CYP3A4 (and thus potentiated by grapefruit juice):

https://en.wikipedia.org/wiki/CYP3A4#CYP3A4_ligands

the substrates box contains the drugs metabolised by the enzyme. If you look in the inhibitors box, you'll see the compounds in grapefruit juice.

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Q: How soon after eating grapefruit can you take medicine?
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I am on Depakote, Clonazepam (Klonopin),Concerta & Prilosec and was concerned about eating grapefruit while on these medications (as I've heard that there can be a negative response while taking some medications and grapefruit together)...~ I just called my pharmacist and listed all these medications for her, and she said that they are ALL FINEto take while eating grapefruit. YAY!~ She went on to say that mostly, there is a concern with taking cholesterol-lowering medications and eating grapefruit. ~ SO, if you are taking: DEPAKOTE, KLONOPIN (Clonazepam), Concerta, or Prilosec (Omeprazole), NO WORRIES! EAT YOUR GRAPEFRUIT & ENJOY!


How grapefruit causes hypertension?

Grapefruit does NOT cause hypertension (high blood pressure) however, if a person already has hypertension and is taking medication for it, they should check with their doctor or pharmacist before eating grapefruit at the same time they take their medication because grapefruit can interfere with how some medications work.


Can you drink medicine after eating shell fish?

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What blood pressure pills should not be taken with grapefruit?

You should take Viagra For high blood pressure, it is good because you can take it with grapefruit. Grapefruit increases the effectiveness of blood pressure pills, therefore, the normal dosage that you take without grapefruit will become an overdose with grapefruit.


What is in grapefruit that makes it interact with medicines?

A daily glass of grapefruit juice or half of a grapefruit for breakfast is normally considered a healthy diet choice: that grapefruit delivers vitamin C, fiber, and potassium. However, grapefruit can be dangerous if taken along with certain of the statin class of cholesterol-lowering prescription medicines.Grapefruit and grapefruit juice interact with multiple prescription medicines, and consuming grapefruit while on these medications can be dangerous. In fact, there are many medications that interact with grapefruit, including the cholesterol-lowering statins Zocor (simvastatin), Lipitor (atorvastatin) and Pravachol (pravastatin).Which Medications Interact With Grapefruit?Grapefruit should be avoided (or minimized - best bet is to discuss with your doctor) when taking a surprisingly broad group of medicines. According to the FDA's Grapefruit Juice and Medicine May Not Mix, grapefruit can interfere with certain of the cholesterol-lowering statins as listed above, some blood-pressure medications, some antihistamines, as well as other drug classes.How Does Grapefruit Interact With Prescription Medicines?Essentially, the juice of grapefruit changes the absorption of certain drugs into the bloodstream. Katherine Zeratsky, a Mayo Clinic Nutritionist, explains, "Problems arise because chemicals in the fruit can interfere with the enzymes that break down (metabolize) the medication in your digestive system. As a result, the medication may stay in your body for too short or too long a time. A medication that's broken down too quickly won't have time to work. On the other hand, a medication that stays in the body too long can increase to potentially dangerous levels, causing serious side effects." For statins in particular, grapefruit juice increases the level of statin in the blood, to a potentially dangerous level.What If I Take My Prescription Hours After Eating Grapefruit?Though eating grapefruit or drinking grapefruit juice hours before or after taking a prescription medicine seems a good strategy, it is not. Shiew Mei Huang, acting director of the Food and Drug Administration's Office of Clinical Pharmacology, explains, "Drinking grapefruit juice several hours before or several hours after you take your medicine may still be dangerous, so it's best to avoid or limit consuming grapefruit juice or fresh grapefruit when taking certain drugs.ConclusionFor those not on prescription medication of any sort, grapefruit and grapefruit juice are a terrific nutritional choice. But if you take any prescription medication - especially statins to lower cholesterol - you should avoid grapefruit and grapefruit juice, or at least discuss with your doctor.Did You Know?Grapefruit juice decreases the effectiveness of allergy medications like Allegra (fexofenadine) by inhibiting the absorption of the drug itself. It may be less effective with apple and orange juice as well, so the fexofenadine label states "do not take with fruit juices."


Can you drink grapefruit juice in morning and take lipitor in evening?

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Can you drink grapefruit juice and take crestor?

Yes you can take grapefruit with tricor. Tricor coming under fibreate family not the statin family. You should limit grapefruit juice and fresh grapefruit consumption while taking statins, as grapefruit can interfere with the liver's ability to metabolize these medications.


Is it safe to eat grapefruit while taking simvastatin?

yes. but you can't take it with grapefruit.


Can you take Sudafed with grapefruit?

Yes. You can take them together.