yes it does
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Grapefruit does interact with Valium. You should use caution when using these together. I recommend not taking Valium within 6-8 hours of eating or drinking grapefruit. The grapefruit can interfere with the way your body metabolizes and uses Valium.
Dilantin
I think, mannitol and phenytoin
is dilantin an opiate
Anytime you are taking multiple drugs, there will be an interaction or a reaction. Be careful.
antiseizure drugs such as phenytoin (Dilantin) and carbamazepine (Tegretol), anticoagulants such as warfarin (Coumadin), and drugs that slow the central nervous system such as alprazolam (Xanax), diazepam (Valium), and secobarbital (Seconal).
I do on a daily basis as directed by my doctor. I take them at night cuz they make me sleepy. I've not had any side effects or any reactions. I'm not a medical doctor & you should always check with your doctor before mixing medications in advance. - Jwseizure
can you take dilantin and somas together
dilantin is used for treating certain types of epileptic seizures.
phenytoin (Dilantin), aspirin, sulfa drugs such as Bactrim and Gantrisin, tetracycline and some other antibiotics and cimetidine (Tagamet). NSAIDs such as ibuprofen (Motrin, Advil) are also known to interact with other classes of antirheumatic drugs.