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ibuprofen will still work if you take it without food, but it is acidic and damages the lining of your stomach. Food dilutes it and prevents it causing damage. It doesn't have to be very much food, a little yoghurt or even a glass of milk will do.

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13y ago
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13y ago

It's recommended to take it after eating, not an empty stomach.

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Wiki User

15y ago

If you take Tylenol on an empty stomach are you likely to get an upset stomach?

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13y ago

Yes. If you don't, you can get ulcers in your stomach.

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12y ago

you should take it with food because it could upset the stomach depending on the sensitivity of the person

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Q: Do you need to take Tylenol with food?
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