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Absolutely! When I had my knee replacement done, I was prescribed Tramadol (or Ultram) and paracetamol (or Tylenol/acetaminophen) in combo. The doses were 50 to 150 mgs of Tramadol (NOT extended release!) with 1,000mg of paracetamol every 4-6 hrs minimum. It worked wonderfully well for me.

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14y ago
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12y ago

I can, but I know what my other medications are. The Valium will relax your muscles and the Tylenol will act as an anti-inflammatory. My Dr. of 20 years prescribed this exact combination recently for my Back pain.

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12y ago

Ask your physician.

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Q: Can you take tramadol with extra strength Tylenol?
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