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Yes, but under special conditions. Your body should be very healthy or this could easily disrupt any balance that the chemicals and ingredients in either drug use to alter the effects on the body. If you are in "ok" shape and eat somewhat wisely, then go for it. If not, or if you aren't sure, I wouldn't advise it. Ask your local doctor if you're able to call or visit if you are very conscious about it. It is smart to check with your doctor before mixing any prescription or non-prescription drugs. - Ph.D, Doctor Adam Borrer

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12y ago
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10y ago

You should not take NyQuil while on Zoloft. If you need to, you should take another kind of OTC cold medication.

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Q: Can you take NyQuil while on Zoloft?
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