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Yes. Pain Mangement doctor's routinely combine Hydrocodone and Flexeril(Cyclobenzaprine) for a better pain relief. Other drugs mixed with hydrocodone to increase its painkilling ability are: Vistaril, Flexeril, Lyrica, Cymbalt and Norflex (the most effective with least effects is Norflex)

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βˆ™ 14y ago
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βˆ™ 16y ago

my doctor prescribed both to me and they seem to be working fine. Ask your doctor if its okay for you.

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Q: Can you mix flexiril and hydrocodone?
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Is flexiril and hydrocodone both pain pills?

Flexiril, is a muscle relaxant, while hydrocodone (usually known as vicodine) is a narcotic pain reliever. So yes, in a way they are both pain pills, but they target different areas.


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you get a good recipe for disaster. dont do it.


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You should not mix painkillers without consulting the physician who prescribed the hydrocodone to you.


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The interaction between hydrocodone and synthetic drugs certainly depends on the specific synthetic drug. It ranges from harmless to lethal.


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