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Both Prozac and Wellbutrin are treatments for depression. Although there are hardly any clinical trials, if any, evaluating response and side effects of the combination therapy some psychiatrists believe the two medications can better handle different components of depression (such as anxiety). Since this is based on personal experiences, not actual systematic testing there is no reliable data on interactions between the two drugs, efficacy or safety.

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Wiki User

16y ago
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13y ago

Yes, I have been prescribed this combination before and they work well together. Prozac deals more with the depression and anxiety, while the wellbutrin will keep you feeling motivated and upbeat, and the seroquel will keep you feeling calm and stable.If you have bipolar like symptoms, serious depression, and high anxiety, this combination has the potential to help you.

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15y ago

This is contraindicated unless under direct doctor supervision. Taking both of these drugs together can increase your risk of seizure tenfold. You will also have more severe side effects from both drugs, since they are so similar. Contact your doctor at once if you become confused, dizzy, or have a seizure.

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10y ago

You can not take Wellbutrin and Prozac together. Both of these medications are known as ssri's and work in the same fashion.

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Jazz

Lvl 1
2y ago
Wellbutrin is not an ssri and does not act directly on seretonin. It acts on the reuptake of dopamine and norepinephrine. Wellbutrin and Prozac are commonly prescribed together.

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15y ago

You can, - I do. Prozac 40mg one time daily and wellbutrin 100mg 2 times daily. Works great !!!

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14y ago

Not unless it's under a doctor's close supervision.

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Jazz

Lvl 2
2y ago

Yes. A psychiatrist will be able to determine if this is the correct combination for you.

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Wiki User

12y ago

YES

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Q: Can you mix Wellbutrin and Prozac?
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