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Methotrexate may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • dizziness

  • drowsiness

  • headache

  • swollen, tender gums

  • decreased appetite

  • reddened eyes

  • hair loss

Some side effects can be serious. If you experience any of these symptoms or those listed in the IMPORTANT WARNING section, call your doctor immediately:

  • blurred vision or sudden loss of vision

  • seizures

  • confusion

  • weakness or difficulty moving one or both sides of the body

  • loss of consciousness

Methotrexate may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

I did not see any Side Effect of diarrhea.

This is a serious drug, any questions you may have, contact your doctor.

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