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I can't find anything online to definitively answer this question, but this was my experienc last night: I took a Zicam before bed, then about twenty minutes later took two Benadry. I woke up hot and cold and twitchy. Then I threw up a ton and felt a lot better. Not sure how much of this was the combo of the medicine or some mystery ailment, but my stomach hasn't bothered me since last night, so I'm inclined to think it has something to do with the medicine I took.

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Q: Can Zicam and Benadryl be safely used together?
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