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While the kidney is normally thought of as an excretory organ, it is also an important endocrine organ (ie, one that produces hormones). One of the hormones it produces is called erythropoietin (EPO), which stimulates the production of red blood cells (RBCs). RBCs are basically sacs of hemoglobin that carry oxygen around. The amount of hemoglobin varies according to the number of RBCs in the blood. And the number of RBCs in the blood is controlled by EPO. In kidney disease, EPO production decreases because the kidney is malfunctioning. As a result, RBC count decreases, as does hemoglobin.

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16y ago
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12y ago

There are more toxins in the bloodstream as the toxins are not getting properly filtered. Hence there are less haemoglobin.

It is actually a result of a lack of EPO Hormone produced by healthy kidneys. The EPO (erythropoietin) is a hormone that stimulates the production of red blood cells in the bone marrow.

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13y ago

iron deficiency

Cobalamin vitamin (B-12)

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Q: Why is there a low hemoglobin level in Kidney Diseased patients?
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