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The body has 23 pairs of chromosomes. There are numbers 1-22, then the 23rd pair are the sex chromosomes. Females have two X chromosomes, making them XX, men have one X and one Y, making them XY.

The principle of a genetic disorder, let's call it "p", is that if someone has one normal, dominant chromosome "P" and one disease-causing, recessive chromosome "p", they are a carrier for the disease, but don't actually suffer from it (effectively the "P" overrides the "p").

Sex-linked disorders are carried on the X chromosome. If a woman inherits one normal X and one X with a recessive disease on it, she will just be a carrier, as she always gets two X's. Men on the other hand are XY, any disease they inherit on their X chromosome will present because they don't have another, potentially normal, X around to override the diseased one.

Hope this helps. :)

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Q: Why is it possible for a man to be a carrier with a recessive genetic disorder but not with a sex-linked disorder?
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Can a person be a carrier for a dominant genetic disorder?

Anyone can be a carrier of a recessive genetic disorder (as long as it is not associated with the sex chromosomes) no matter what their gender since "carrier" refers to an individual that is heterozygous for the recessive allele and therefore phenotypically normal. Specifically, sexlinked genetic disorders can be "carried" by a heterozygous female but males (having only one X chromosome) cannot. Males will either be free of the defective gene or be affected.


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