The old Total T4 test (TT4) is no longer considered the best way to test for T4 levels. T4 and T3 can both be bound by other proteins and hormones in the body. When this happens, the T4 or T3 is not usable by the body. The body can only use T4 and T3 that is not bound, or free. For this reason, Free T4, which only tests the free levels of the hormone, is now preferred over Total T4 testing as more accurate.
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