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Females are not more likely to get Down's syndrome.

Down's syndrome is slightly more common among males with most studies showing about 106 to 125 boys for every 100 girls.

In some studies younger mothers, who have a lower total chance of having a baby with Down's syndrome, have a more skewed male:female ratio when they do (as high as 173 boys for every 100 girls).

No one is sure why boy are affected more often.

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13y ago
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14y ago

It is known that females are more likely to be afflicted with spina bifida, but the reason is not known.

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14y ago

For some unknown reason spina bifida is more common in females.

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14y ago

Females. See the Related link below.

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Q: Why are females more likely to get Down syndrome than males?
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Is down syndrome most common with females?

Down Syndrome is spread fairly evenly between males and females. There does seem to be a slightly higher incidence among males, however.


Are people with Down syndrome sterile?

50% of females with Down syndrome are able to conceive children, while males with Down syndrome are usually sterile.


Would a male with Down syndrome and a male without Down syndrome have a child with Down syndrome?

== == * I did some research and learned that men with Down syndrome are usually sterile. Most women can get pregnant and have children. Since there is a high risk of Down syndrome in the baby (35%-50%), many times the pregnancy would end in a miscarriage. But many Down syndrome people have had children. * Technically yes, but it's unlikely. Fertility is greatly reduced in both males and females with Down syndrome, although there have been a few cases of males fathering children and females bearing them. * Actually, there has only been 1 case of a male fathering a child. A women with Down syndrome can have children, but there is a 50% chance that the baby will be born with Down syndrome.


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