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What is allogeneic bone marrow transplantation?
In a procedure called "allogeneic bone marrow transplant," a donor is found whose marrow matches that of the patient.
What kind of bone marrow transplantuses bone marrow from a doner?
All bone marrow transplants require bone marrow from a donor; the purpose of the transplant is to replace the patient's bone marrow (that no longer works) with some that does work, which clearly cannot come from the patient (since they have none that works). Hence a donor must be used.
What type of bone marrow transplant usues bone marrow from a donor?
allogenic
What is Marrow replacement process?
This is bone marrow transplant. A compatible donor should be screen and crossmatch before they can perform the transplant.
Has leukemia and requires a bone marrow transplant part of the treatment was the harvesting of her bone marrow so she could receive it later as a?
In a bone marrow transplant, the patient receives healthy stem cells to replace their damaged or diseased bone marrow. The harvesting process involves collecting these healthy stem cells from either the patient (autologous transplant) or a donor (allogeneic transplant). The harvested cells are then given back to the patient after undergoing certain treatments to help rebuild their immune system and blood cells.
What is the bone marrow transplant uses healthy bone marrow cells from a compatible donor such as a sibling?
Sometimes. In an allogeneic bone marrow transplant the bone marrow is taken from a donor and infused into a recipient. Usually the recipient has undergone intensive radiation therapy in order to wipe out the immune system so that it will not attack the foreign bone marrow cells (reject it) and the donor marrow has had some cells that would attack the recipient removed. In an autologous transplant bone marrow is removed from the patients, treated in some way, and then infused back into the patient. It can be frozen and saved while the patient undergoes some kind of therapy and then thawed and reinfused. In a syngeneic transplant marrow from one identical twin is infused into the other twin. This one is pretty cool because no treatment is needed to prevent rejection (but the recipient will probably still receive treatment for the disease.
Some Facts About Bone Marrow Transplant?
A bone marrow transplant is the transplant of marrow cells and blood from a healthy person to a person who is in need of marrow and blood cells. The healthy blood and marrow replace the diseased cells of the sick person. The marrow cells are stem cells, which means they can develop into red blood cells, white blood cells and platelets.Who Needs a Bone Marrow Transplant?People who have blood cancers like leukemia may need bone marrow transplants. Leukemia is a malignant overgrowth of white blood cells in the bone marrow, the lymph glands, the spleen, the liver or other organs that are part of the lymphatic system. Other candidates for the transplant are:People whose suffer from thalassemias, where the red blood cells contain less hemoglobin than normal.People who suffer from aplastic anemia, where the bone marrow doesn't produce enough blood cells.People who suffer from sickle cell anemia, where the red blood cells are deformed and can't carry hemoglobin properly. Sickle cell anemia causes episodes of extreme pain and chronic poor health and can be life threatening.Sometimes radiation and chemotherapy can damage bone marrow to the point where it can't produce blood cells, so a bone marrow transplant is needed.Who Gives a Bone Marrow Transplant?The patient can give a bone marrow transplant to themselves. If the patient was healthy and had to have treatment where the destruction of their bone marrow was a possibility, they can have their bone marrow stem cells stored.Other bone marrow transplants come from a donor. The problem here is that the donor's stem cells have to match the patient's very closely. Sometimes, even a brother, sister or parent isn't a match for the patient and there might be a wait till a donor is found.Sometimes the donor cells come from umbilical cord blood.How Is Bone Marrow Collected?Nowadays, doctors rarely perform the painful procedure where marrow is taken out of the donor's hip, but in most cases a needle withdraws blood from the donor's arm. The stem cells are removed from the blood and what's left of the donor's blood is returned to them.
What bone marrow is used in a bone marrow transplant?
In a bone marrow transplant, the bone marrow used typically comes from a donor who matches the recipient's tissue type. This matching helps reduce the risk of rejection. The bone marrow is usually harvested from the donor's hip bones using a needle.
How many types are there of bone marrow?
There are three types of bone marrow transplant procedure. One of the three is called an Autologous bone marrow transplant. With an Autologous bone marrow procedure, doctors take the persons own bone marrow and freeze it before chemo then reintroduce the marrow into red blood cells after chemo or radiation. The second type is Allogeneic. In an Allogeneic marrow procedure the marrow is taken from a matching marrow donor. The third type is called Umbilical cord blood transplant. With an umbilical cord blood transplant, there can be a wider variety of donor as the cells are still considered immature.
What type of bone transplant uses bone marrow from a donor?
Either a bone marrow or a stem cell transplant (although these days most stem cell transplants are obtained from blood).
Can a bone marrow biopsy determine if you are compatible for a bone marrow transplant?
Yes, a bone marrow biopsy can determine if the donor and recipient are compatible for a bone marrow transplant. This involves analyzing the human leukocyte antigen (HLA) markers present in the bone marrow cells of both the donor and recipient to assess compatibility. Matching these markers increases the chances of a successful transplant.
What is a bone marrow match?
A bone marrow match is when a person's human leukocyte antigen (HLA) tissue type matches that of a patient in need of a bone marrow transplant. This matching is crucial to reduce the likelihood of rejection and improve the success of the transplant. Finding a compatible donor is essential for the patient's body to accept the new bone marrow and start producing healthy blood cells.
