Down syndrome (trisomy 21) occurs when a gamete carrying an extra copy of chromosome 21 is involved in a fertilization event.
The gamete (whether sperm or oocyte) has an extra copy of chromosome 21 because of something called NONDISJUNCTION. This happens when a chromosome gets pulled to the wrong daughter cell.
This can happen either in meiosis I or meiosis II.
If nondisjunction happens in meiosis I, 2 gametes will be n+1 (have the extra copy of 21) and the other 2 gametes will be n-1 (will have NO copy of 21)
If nondisjunction happens in meiosis II, 2 gametes will be normal, one will be n+1 and one will be n-1.
Division occurs in the M phase of the cell cycle, which includes mitosis (nuclear division) and cytokinesis (cytoplasmic division).
Interphase occurs in the cell cycle, between cell divisions. It is the stage in which the cell grows, carries out its normal functions, and prepares for cell division.
DNA replication occurs during Interphase. This is not normally part of the cell division cycle but interphase must occur before subsequent stages such as prophase and metaphase can occur.
Nuclear division does not occur during interphase. Interphase is a stage in the cell cycle where the cell grows, carries out its normal functions, and replicates its DNA in preparation for cell division. Nuclear division occurs during other stages of the cell cycle, such as mitosis or meiosis.
tatanga tngahan
No. Gene therapy alters a person's genetic code, generally by inserting a genetic sequence. Trisomy 21 (downs syndrome) is caused by the presence of a copy (or part of a copy) of the 21st chromosome. Genetic therapy would not be able to remove this extra chromosome. It might be possible (in the future) to "turn off" the extra chromosome, and stop trisomy-21 at the embryo stage. However, by the time a person is born, the physical damage from downs syndrome has been done. After a few months to a year or so, the mental damage from downs syndrome will also be done. So no "treatment" for downs syndrome will be possible using genetic modification such as gene therapy.
expulsion stage
stage 4
alarm stage
Preparation for cell division occurs during the interphase stage of the cell cycle. This is when the cell grows, carries out normal functions, and replicates its DNA in preparation for division.
interphaseprophaseanaphasetelophasecytokinesis
A.) Resistance stage