Not much difference. They are both strains of the HIV virus and both can lead to AIDS and other opportunistic diseases. HIV-2 strain is found mostly in West Africa, with hardly any found in the US and other Western countries.
Both HIV-1 and HIV-2 are equally "dangerous" in that both are sexually transmitted and both lead to AIDS. There are several difference between the two, in terms of how transmissible they are and how each progressess. The bottom line--you want to avoid either type of the virus.
HIV 1 can cause fever, headache, fatigue, swollen lymph glands, and a rash. HIV 2 can cause all of those plus confusion, diarrhea, mouth sores, stiff muscles, forgetfulness, and night sweats.
Because no whole cells of HIV have ever been isolated from human tissues. In theory, a retrovirus known as HIV1 and its variant HIV2 cause Acquired Immune Deficiency Syndrome, but as yet, it has not been isolated as a whole cell. A culture can only start with actual cells, not theoretical ones.
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