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Leukemia is a disease in which uncontrollably dividing blood cells invade the bone marrow and circulating blood. The cause is a defect in control of the cell cycle which allows the cell to go on dividing unchecked. The precipitating factors for this loss of control of the cell cycle are many.

The exact cause of leukemia is unknown but is influenced by both genetic and environmental factors. Leukemias, like other cancers, result from somatic mutations in the DNA which activate oncogenes or inactivate tumour suppressor genes, and disrupt the regulation of cell death, differentiation or division. These mutations may occur spontaneously or as a result of exposure to radiation or carcinogenic substances and are likely influenced by genetic factors.

Cohort and case control studies have linked exposure to petrochemicals, such as benzene, and hair dyes to the development of leukemia. Viruses have also been linked to some forms of leukemia. Certain cases of ALL are associated with viral infections by either the human immunodeficiency virus (HIV, responsible for AIDS) or human T-lymphotropic virus (HTLV-1 and -2, causing adult T-cell leukemia/lymphoma). Fanconi anemia is also a risk factor for developing acute myelogenous leukemia.

There are a number of different kinds of leukemia, and they may have different causes. What is clear is that the causes of leukemia are unclear. There are some good arguments made for increased risk of leukemia based on genetic predisposition(it "runs in your family"), some viruses, exposure to some kinds of chemicals and also exposure to ionizing radiation, either natural or artificial. Leukemia is a form of lymphoma (cancer), and we're still on the trail in an attempt to nail down actual causes. A link is provided to the Wikipedia article on leukemia.

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12y ago
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14y ago

There are a number of different kinds of leukemia, and they may have different causes. What is clear is that the causes of leukemia are unclear. There are some good arguments made for increased risk of leukemia based on genetic predisposition(it "runs in your family"), some viruses, exposure to some kinds of chemicals and also exposure to ionizing radiation, either natural or artificial. Leukemia is a not-so-nice form of lymphoma (cancer), and we're still on the trail in an attempt to nail down actual causes. A link is provided to the Wikipedia article on leukemia.

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14y ago

About one thousand years ago an a bomb was dropped and

that bomb was filled I think it was filled with some type of poison made millions of people sick and their blood cells in your body the get infected and millions of people died its very rare if you survive leukemia.

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13y ago

when the blood cells mutate into cancer cells. blood cancer is called leukemia.

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13y ago

It is caused by adult t cells children have had it and adults have it 256,000 people all over the world were affected by leukemia and 209,000 people were killed by it

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12y ago

when the rbc cont in blood increases

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12y ago

cancer

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Q: What is the cause of leukemia?
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