Hypersensitivity describes associate abnormal or pathologic reaction that's caused by associate immunologic response to perennial exposure to associate matter. Hypersensitivity diseases embrace response diseases, during which immune responses area unit directed against self-antigens, AND diseases that result from uncontrolled or excessive responses to foreign antigens. as a result of these reactions tend to occur against antigens that can't be loose (i.e. self-antigens) and since of regeneration systems intrinsic to numerous aspects of the immunologic response, hypersensitivity diseases tend to manifest as chronic issues.
This question requires a complex answer. The following is an oversimplification.
An antigen is a substance which causes the body to create an immune response. That is, having once contacted the substance the body builds up a resistance to its effect. Vaccines are based on this. They give you a mild introduction to the antigen and your body builds up an immunity to it such that when you are exposed to it later is has no reaction or a reduced reaction. A hypersensitivity response is when the immune system overreacts to the antigen and does destructive things to organs that can be minor or cause death.
There are four types of antigen hypersensitivity responses that operate in different was on the body.
Hypersensitivity to a second dose of antigen.
hypersensitivity
It is an allergy
An Arthus reaction is a hypersensitivity reaction involving the in situ formation of antigen/antibody complexes after the intradermal injection of an antigen.
Anaphylaxis is the term that describes an exaggerated life-threatening hypersensitivity reaction to a previously encountered antigen. It can lead to symptoms such as difficulty breathing, swelling, and a drop in blood pressure, requiring immediate medical attention.
Delayed hypersensitivity reactions, also known as type IV hypersensitivity reactions, are caused by T cells recognizing antigens and triggering an immune response. This can happen hours to days after exposure to the antigen. Common triggers include certain drugs, metals, and infectious agents.
Delayed hypersensitivity reactions are immune responses that occur several hours to days after exposure to an antigen. They are mediated by T cells rather than antibodies, leading to the release of inflammatory mediators and recruitment of immune cells to the site of antigen exposure. Examples include contact dermatitis, tuberculin skin tests, and some drug reactions.
Hypersensitivity Type II involves antibodies targeting self-antigens on host cells, leading to cell destruction. In contrast, Type III hypersensitivity involves immune complexes formed by antigen-antibody interactions that deposit in tissues, causing inflammation and tissue damage.
An allergy is a hypersensitivity to an environmental antigen (allergen). If a person has a hypersensitivity to an antigen they will have a patholigic (disease) response when exposed to that antigen. When the hypersensitive individual is initially exposed to the antigen, they will produce allergen specific antibodies, primarily immunoglobulin E (IgE), that will during subsequent exposures bond with membrane proteins on the mast cell membrane. This bonding allows degranulation (the release of stored chemicals) of the mast cell. Mast cells manufacture and store chemicals, including histamine, that are responsible for the affects of inflamation.
A transfusion reaction is typically an acute hypersensitivity reaction to foreign red blood cells, which can occur immediately or within a few hours of the transfusion. Subacute hypersensitivity reactions usually take days to develop after exposure to the antigen, unlike the immediate onset of symptoms seen in transfusion reactions.
Some more context would be helpful. This question sounds like it may be asking about antigen exposure in the field of allergic disease, but it's hard to be sure. Hypersensitivity reactions (the immune system basis for allergies) are based on the principle that allergy follows initial sensitization to an antigen.
The accented syllable in "Hypersensitivity" is "-sen-".