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The acquired immune response is also known as the specific immune response. This involves the presentation of micro organisms antigens by macrophages to T and B lymphocytes (T and B cells). T cells and B cells specific to these antigens will then go through clonal expansion (mass production) to help carry out a specific response that has been 'acquired' as a direct result or particular microorganisms antigens.

T cells are divided into T helper and T killer, and B cells into memory cells and plasma cells.

T helper cells aid B cells in their production and carrying out their functions. T killer cells kill infected cells (those containing viruses or bacteria, as detected by their presentation of antigen on MHC Class 1 receptor molecules on their surface).

B cells differentiate into plasma cells and memory cells, plasma cells produce antibodies specific to the type or types of antigens detected. Memory cells have the ability to live for long amounts of time and quickly differentiate into plasma cells should the same antigens present at a later date, allowing a faster and more efficient immune response if infected again with the same microorganism.

The acquired immune response usually takes 7-10 days after initial presentation of the antigens by macrophages - unless this is a secondary response, in which case the person should have already produced memory cells so can deal with the invading microorganisms faster and more efficiently.

The innate (passive) immune system is responsible for initial responses, this is non specific and involves neutrophils largely.

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Q: What is acquired Immune Response?
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What is the difference between the innate immune response and the acquired immune response?

The innate immune response is the body's first line of defense against pathogens and is non-specific, meaning it does not target specific pathogens. It includes physical barriers like skin and mucous membranes, as well as immune cells like macrophages and natural killer cells. The acquired immune response is more specialized and involves the activation of immune cells such as T and B lymphocytes that target specific pathogens based on memory from past exposures.


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The innate immune response is the body's immediate, non-specific defense mechanism against infections. It is always ready to respond to invaders. The acquired immune response is specific to a particular pathogen and involves the production of antibodies and memory cells for long-term protection. It takes time to develop but provides a targeted defense against specific pathogens.


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