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Megaloblastic anemia has many causes. Among them is a vitamin B12 deficiency which can be an issue in the DNA of a person. Another is outside factors, like Alcoholism, or a drug interferes with the absorption of folic acid. It could also happen if a woman becomes pregnant and they are no longer getting the folate they need to support themselves and the baby.
Megaloblastic anemia is a blood disorder in which there is anemia with larger-than-normal red blood cells.
Anemia is a condition in which the body does not have enough healthy red blood cells. Red blood cells provide oxygen to body tissues.
Alternative NamesAnemia - megaloblastic
Causes, incidence, and risk factorsMegaloblastic anemia is usually caused by a deficiency of folic acid or vitamin B12.
Other less common causes are:
- Alcohol abuse
- Certain inherited disorders
- Drugs that affect DNA, such as chemotherapy drugs
- Leukemia
- Myelodysplastic syndrome
- Myelofibrosis
Risk factors relate to the causes.
See also:
SymptomsSee:
Signs and testsFor testing information, see:
TreatmentThe first goal is to diagnose the cause of the anemia. The treatment depends on the cause. Anemias related to specific vitamin deficiencies are discussed separately.
See:
ReferencesAntony AC. Megoblastic anemias. In: Hoffman R, Benz EJ, Shattil SS, et al., eds. Hematology: Basic Principles and Practice. 5th ed. Philadelphia, Pa: Elsevier Churchill Livingstone; 2008:chap 39.
Kaferie J, Strzoda CE. Evaluation of macrocytosis. Am Fam Physician. 2009;79:203-208.
Megaloblastic anemia is a blood disorder in which there is anemia with larger-than-normal red blood cells.
Anemia is a condition in which the body does not have enough healthy red blood cells. Red blood cells provide oxygen to body tissues.
Alternative NamesAnemia - megaloblastic
Causes, incidence, and risk factorsMegaloblastic anemia is usually caused by a deficiency of folic acid or vitamin B12.
Other less common causes are:
- Alcohol abuse
- Certain inherited disorders
- Drugs that affect DNA, such as chemotherapy drugs
- Leukemia
- Myelodysplastic syndrome
- Myelofibrosis
- The anticonvulsant drug dilantin
Risk factors relate to the causes.
See also:
SymptomsSee:
Signs and testsFor testing information, see:
TreatmentThe first goal is to diagnose the cause of the anemia. The treatment depends on the cause. Anemias related to specific vitamin deficiencies are discussed separately.
See:
ReferencesAntony AC. Megoblastic anemias. In: Hoffman R, Benz EJ, Shattil SS, et al., eds. Hematology: Basic Principles and Practice. 5th ed. Philadelphia, Pa: Elsevier Churchill Livingstone; 2008:chap 39.
Kaferie J, Strzoda CE. Evaluation of macrocytosis. Am Fam Physician. 2009;79:203-208.
Reviewed ByReview Date: 05/09/2011
A.D.A.M. Editorial Team: David Zieve, MD, MHA, and David R. Eltz. Previously reviewed by Yi-Bin Chen, MD, Leukemia/Bone Marrow Transplant Program, Massachusetts General Hospital (1/31/2010).
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What is a megaloblastic anemia resulting in a decrease of hydrochloric acid?
Pernicious anemia
Does drinking for over a year lead to anemia?
Alchohol can be associated with anemia. For example, alcoholic liver damage can be a cause of megaloblastic anaemia Alchohol can be associated with anemia. For example, alcoholic liver damage can be a cause of megaloblastic anaemia
A deficiency of vitamin b12 leads to which type of anemia?
Megaloblastic (Macrocytic) Anemia. Basically the Red Blood Cells have a larger volume (MCV).
What is megaloblastic?
Megaloblastic anemia is a blood disorder. It is marked by the appearance of very large red blood cells in addition to anemia, which involves the loss of red blood cells that transport oxygen through the body.
Is a megaloblastic anemia resulting in a decrease of hydrochloric acid?
_ is caused by protozoan plasmodium
When does vitamin B12 anemia occur?
Vitamin B12 deficiency anemia is another type of megaloblastic anemia that develops when the body doesn't absorb enough of this nutrient.
What best describes the characteristics erythrocyte associated with pernicious anemia?
megaloblastic or macrocytic nucleatd cells.
Megaloblastic anemia results from a deficiency of?
Megaloblastic anemia results from a deficiency of vitamin B12 or folic acid, both of which play a crucial role in DNA synthesis and red blood cell production. This deficiency leads to the production of abnormally large and immature red blood cells, causing anemia.
What is the icd 9 code for anemia?
Macrocytic anemia is under 281.9 in the ICD-9. Macrocytic anemia does not have its own code. It shares that code with several other types of unspecified deficiency anemia, including dimorphic, megaloblastic NOS, nutritional NOS, and simple chronic.
What is the connection between hypercellularity in bone marrow and megaloblastic anemia?
Megaloblasitc anemia refers to the abnormal enlargement of RBCs rendering them useless and subject to hemolysis, therefore the bone marrow must up regulate its hematopoietic stem cell production and in particular the differentiation of reticularcytes to counter the anemia.
What condition is caused by lack of vitamin b12?
Deficiency leads to pernicious anaemia when immature red blood cell precursors are released into the bloodstream, and there is degeneration of the spinal cord.
What is the ICD-9 code for macrocytic anemia?
Macrocytic anemia is under 281.9 in the ICD-9. Macrocytic anemia does not have its own code. It shares that code with several other types of unspecified deficiency anemia, including dimorphic, megaloblastic NOS, nutritional NOS, and simple chronic.
