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A: In sickle cell disease, red blood cells contain an abnormal form of hemoglobin, or hemoglobin S. As the red blood cell deoxygenates, hemoglobin S forms cross-links with other hemoglobin S molecules, and long crystals develop. Crystals continue to form as oxygen is released, and the red cells assume a sickled shape. Sickled red blood cells are inflexible and rigid and cause mechanical obstruction of small arterioles and capillaries, leading to pain and ischemia.
This can result in Heart disease, stroke and characteristic symptoms of sickle cellanemia such as pain and swelling of the hands and feet.
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Is it safe to marry a person with sickle cell?
it is safe to marry a person with sickle cell, provided that you are not a career of the trait.
What groups get sickle cell disease?
A person can only inherit sickle-cell genes if some of their ancestors came from certain regions in Africa where the inhabitants carry sickle-cell genes. A person with one sickle-cell gene has sickle-cell trait, a milder problem. If both father and mother pass on sickle-cell genes, the child, with two genes, will have sickle-cell disease.
How does a person with one sickle cell different than two Sickle cell?
A person with one sickle cell is a "carrier". This means that they have the dormant cell in their genetic composition, and if combined with another with the "carrier" gene, they run the high risk on concieving a child with the blood disease-one who has two sickle cells. A person with two sickle cells, has the sickle cell disease and are carriers(The gene is not dormant but active). Hope this simplifies and explains it for you.
Where in the world are the most cases of Malaria and Sickle Cell anaemia?
Malaria is common in topical ad subtropical zones. The malaria has selected the people with sickle cell anaemia. Although person with sickle cell anemia can have malaria, the carrier, or the person with sickle cell trait is resistant to malaria.
What is requires for a person to have sickle cell disease?
The person is homozygous for the trait
If Natasha has normal blood cell but marries someone who has sickle cell trace What are the chances of them having a child with sickle cell?
If a person does not carry the Sickle cell trait and they marry some one with the trait. The child that comes from that relationship can never have sickle cell disease, however that child has a chance of having the sickle trait.
What is the ESR in a person with sickle cell anemia?
0mm
What is require for a person to have sickle-cell disease?
The person is homozygous for the trait
How does a person with sickle-cell allele differ from a person with two sickle-cell alleles?
If a person has a single sickle cell allele they will have some sickles red blood cells, and some normal red blood cells. This is the origami purpose that this evolved for. If a person had a single sickle cell allele, they will be mostly resistant to malaria. This is why sickle cell anemia is most prevalent in areas of the world where malaria is common. However, if a person has two sickle cell anemia alleles, they will have ONLY sickled red blood cells. The "sickling" of the red blood cells is caused by a mutation in the protien that the gene codes for. That protein is hemoglobin, which carries oxygen through the blood. If a person has sickle cell anemia, parts of their body wil not get enough oxygen. They can pass out, loose sensation in the limb, or even die from it. In short, a person with two alleles is sick, and a person with one allele is not.
What is required for a person to have sickle cell?
The person is homozygous for the trait
What is it called when a person has two recessive alleles for sickle cell trait?
A person with two recessive alleles for sickle cell trait has sickle cell anemia. This genetic condition leads to the production of abnormal hemoglobin, causing red blood cells to become sickle-shaped and leading to various health issues.
What is a sickle cell?
a person who receiver traits from anothr karyotype
