Lymphoma is a cancer that affects the lymph system, which is a sort of transportation network that carries infection fighting white blood cells throughout the body. Lymphoma presents various symptoms that are frequently mistaken for an infection. The most common symptom a person notices is an enlargement of the lymph nodes in areas of the body ranging from the groin, neck, or armpit area. It is described as a lump. Appetite and weight loss also occur, along with fever, excessive sweating, lethargy, itching and shortness of breath. In addition, other organs can become affected. The spleen could become enlarged, causing stomach pain or an early feeling of fullness. Arms and legs can experience swelling and in some instances tingling and numbness occurs.
Two types of lymphoma exist: Non-Hodgkin's and Hodgkin's. The differences occur within the type of lymphocyte cell the cancer derives from. Lymphocytes filter infectious organisms and fight illness. There are two types of lymphocytes: types B and T. Hodgkin's comes from abnormal B lymphocytes. Non-Hodgkin's can derive from abnormal T or B lymphocytes that have distinguishable features that doctors can differentiate between. In order to properly diagnose lymphoma, doctors run a battery of tests so that they can pinpoint the severity, location, stage and prognosis of the cancer. Tests include blood work, x-rays, scans and biopsies. In some cases, bone marrow tests may also be necessary. The various exams help doctors ensure they properly stage the lymphoma. The stages run from I to IV. The letters "A" and "B" are also added to the diagnosis. "A" means no typical symptoms are present; "B" means symptoms are present.
Treatment for lymphoma involves the use of chemotherapy and radiation. It varies depending on a person's health and age. Although the causes of any kind of cancer are not specifically known, researchers do know what risk factors are associated with different cancers. Some of the risk factors linked to lymphoma include old age, infections such as HIV, Epstein-Barr virus, H. Pylori, and hepatitis, other diseases that cause the immune system to become weak, genetics, and exposure to some chemicals. In order to improve the possibility of remission, it is important to have yearly physical exams and to see a doctor whenever signs of illness arise. Early detection is key to fighting cancers like lymphoma.
Patients may experience loss of appetite, weight loss, nausea, vomiting, abdominal discomfort, and indigestion.
At present, there are no special tests that are available for early detection of non-Hodgkin's lymphomas.
The plural of lymphoma is lymphomas.
The exact cause of non-Hodgkin's lymphomas is not known.
Bone marrow transplantation is used in cases where the lymphomas do not respond to conventional therapy, or in cases where the patient has had a relapse or suffers from recurrent lymphomas.
Enlargement of the lymph nodes, liver, or spleen may suggest lymphomas.
A majority of non-Hodgkin's lymphomas begin in the lymph nodes.
MALT lymphomas occur at a frequency of about 1.5 per 100,000 people per year in the United States and account for about 10% of all non-Hodgkin's lymphomas.
B cell lymphomas are more common among adults, while among children, the incidence of T and B cell lymphomas are almost equal.
MALT lymphomas are generally indolent, that is, they grow slowly and cause little in the way of symptoms.
It is not known if infectious agents also cause MALT lymphomas outside of the stomach.
MALT lymphomas are then recognized as areas of inflammation or ulceration within the stomach.
Because there is lymph tissue in many parts of the body, lymphomas can start in almost any organ of the body.