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Sinusitis is not a simple matter-- not a thing to simply be cured or

not by the right antibiotic (although it is sometimes that simple).

Bacteria grow in sinuses not draining correctly, and the question is

why they aren't? Anatomical problems, Allergies, what? Then there is

the problem that chronic sinus infections cause their own damage, and

tend to be mixed infections with anaerobes and even fungi.

Finally, there is the problem that there are many things not known

about this area. For instance, I've seen two people on high dose IV

mega antibiotics for hospital infections, who were also as a side

effect "cured" of nearly life long "seasonal allergies" thereby.

Apparently. What was going on there? I dunno.

If one has to treat chronic sinusitis with antibiotics alone, it's

probably best to try a regime with clindamycin in it, to get the

anaerobes, and metronidazole so the clinda doesn't cause C. difficile

for the 6 weeks you're going to be taking it. After that, it's a

tossup what broad-spectrum antibiotics to try, except that they need to

cover H. flu and strep and perhaps staph. Macrolides are not going to

be helpful if you're already using clindamycin, so Biaxin and Zithromax

are not great ideas. Augmentin or a fluoroquinolone can be used.

Rifampin is also sometimes very helpful as adjunct in getting at deep

seated infections with lots of pus (as in sinuses).

Quite often the main thing, however, is to see the ENT people about

drainage, and the allergy people about desensitization.

J.Fisher

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13y ago
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14y ago

Doxycycline is the antibiotic most widely prescribed for sinal infection. Also used for long term malarial protection as does not cause renal/kidney problems associated with other anti malarial prophylaxis.........although can cause sunlight sensitivity which may be a problem in a sunny tropical climate!

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13y ago

Sinus infections can be treated by a number of antibiotics. The most common are amoxicillin, augmentin, bactrim, zithromax and biaxin. The choice has more to do with the severity of the infection and the patient history (allergies to medications, etc).

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13y ago

Probably one of the anti bacterial ones and not the viral antibiotics.

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Q: What antibiotic is commonly used for a sinus infection?
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No. Acyclovir should not be used to treat a sinus infection. Acyclovir is an antiviral drug used to treat herpes. Sinus infections are bacterial and require an antibiotic.


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The drug is an antibiotic and used to treat infections.


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