effect of serotonin in vascular system
Imbalances in serotonin (a neurotransmitter) are thought to play a part in Migraine genesis.
Depression is due to alteration in the level of serotonin at the synaptic junctions of neurons in the limbic system.
The inflammatory response is part of the immune system. It is a response by the body to a particular infection, injury or disease. Inflammation is characterized by a reddening of the skin, pain, heat and swelling.
I can partly answer this question: Basophils, which are granular leukocytes, are a part of our bodies natural makeup, they produce heparin (an anticoagulant), histimines (an inflammatory substance), and serotonin (a vasoconstictor).
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Serotonin can have both excitatory and inhibitory effects depending on the receptor type and the specific brain region. Generally, serotonin is known to have mainly inhibitory functions in the central nervous system.
Breathing is not an inflammatory process. An inflammatory process is where the body's immunity system through the white blood cells will respond to a particular injury.
Serotonin is a brain chemical which we all have in our brains. It has 3 actions in the brain: 1. It gives us self-confidence, a feeling of safety and security. 2. It causes us to feel sleepy. 3. It increases our appetites. The part of the brain where it does each of these 3 things is a different part of the brain from the part where the other 2 things occur. Thus, for example, increasing serotonin in the part of the brain where self-confidence is will increase your self-confidence, but not your sleepiness. Unfortunately, we have no medications to increase only the serotonin in one part of the brain. This explains why medications to increase serotonin in the brain can also cause increased appetite and sleepiness. Medications which increase serotonin in the brain (SSRI's such as citalopram, escitalopram, fluoxetine, paroxetine, and sertraline and SNRI's such as venlafaxine and duloxetine) give us more self-confidence, and a feeling of safety and security. By the way, serotonin also exists in our gastrointestinal tracts. In this location, it stimulates digestion. This is why such medications can cause gastrointestinal upset. But they can also help constipation.
The target organs of serotonin include the brain, where it regulates mood, appetite, and sleep, as well as the gastrointestinal tract, where it influences gut motility and function. Additionally, serotonin plays a role in the cardiovascular system, affecting blood clotting and vessel constriction.
the Frontal Cortex
Without an inflammatory response, the body would have difficulty fighting infections and healing injuries. Inflammation is a crucial part of the body's immune system and helps to remove harmful stimuli and initiate the healing process. A lack of inflammatory response could lead to severe infections or delayed healing.