Function and structure of tissue plasminogen activator?
Tissue plasminogen activator (tPA) is an enzyme that plays a crucial role in the breakdown of blood clots by converting plasminogen into plasmin, which breaks down fibrin, the key protein in blood clot formation. tPA is primarily produced in endothelial cells and is released in response to blood vessel injury. Its function is to maintain proper blood flow and prevent clot formation in blood vessels.