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If it is a denture that was made the same day the teeth were extracted, after about 6 weeks, you should have the denture relined. People usually don't want to walk around with out teeth while the bone and tissue heals. So an immediate denture is made. After the swelling goes away the tissue may shrink causing the denture to be sort of loose. This is when it is time to have it relined. Dental adhesive, in my opinion, should be a last resort. If it is a partial instead of a full denture, the person who made it should be able to adust it so the claps hold it in place without having to use adhesive.

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Q: If you have a new dental plate when do you have to start using dental grip?
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