It really depends about the stage and severity and whether or not a treatment is being taken. Many people live long, eventful lives with Ankylosing Spondylitis with treatment and excercise.
Ankylosing Spondylitis is an Autoimmune Disease that concerns itself mostly with your spine and trying to fuse the bones there together. Seizures are caused by a misfiring in the brain, so as far as I know (and I've done exstensive research in the Autoimmune Disease area) no, it cannot. Seizures are not a symptom of Ankylosing Spondylitis. Some pain medications can cause seizures (like Tramadol) and many diseases affect the brain. (MS, Encephalitis, etc.) but I can pretty much assure you that Ankylosing Spondylitis does not.
the causes for ankylosing spondolytis are not known as is the case with many form of arthritis. There seems to be anassociation with a gene called HLA--B27.Nearly nine of ten people with AS test positive for this gene. However this is a normal gene and only one in twenty people who have it will develop AS. It is more likely to happen if there is a history of it in your family.
Ankylsing Spondylitis (AS) is a chronic inflammatory autoimmune disorder. It is an arthritic condition generally affecting the spine although it may also affect large joints such as knees, jaw, ankles, and shoulders. As can also attack the rib cage, limiting chest expansion and inhibiting breathing. It ususally affects males 17 to 22 years of age. It is also found among the female population. AS is mostly found among the population with B+ blood and a gene called hlaB27. This is found by taking a blood sample. Diagnosis of AS is a process of eliminating other conditions that are similar in appearance. AS is also called 'the great imitator' as the condition may resemble many conditions including cancer and multiple sclerosis. A patient may be diagnosed by taking x-rays and a simple blood test. AS can also attack internal organs around the spinal region of the body and can cause secondary conditions such as hammer toe and iritis. Over time, the spine or other joints may fuse together causing what is known as 'poker spine' and the person will not be able to bend over at all. The condition can become debilitating but not often fatal. The disorder can cause other autoimmune and chronic disorders that may lead to fatalities due to kidney disease or swollen heart. Some patients have been known to die from medications used to treat the illness. The presence of hlaB27 does not mean the person will develope AS but the gene is found in over 97% of sufferers with AS. People with AS should keep x-rays to a minimum as this has been shown to be contradictory in some people and may cause leukemia.
DefinitionAnkylosing spondylitis is a long-term disease that causes inflammation of the joints between the spinal bones, and the joints between the spine and pelvis. It eventually causes the affected spinal bones to join together.See also: ArthritisAlternative NamesRheumatoid spondylitis; Spondylitis; Spondylarthropathy; Seronegative bundle arthropathyCauses, incidence, and risk factorsThe cause of ankylosing spondylitis is unknown, but genes seem to play a role.The disease most often begins between ages 20 and 40, but may begin before age 10. It affects more males than females. Risk factors include:Family history of ankylosing spondylitisMale genderSymptomsThe disease starts with low back pain that comes and goes.Pain and stiffness are worse at night, in the morning, or when you are not active. It may wake you from your sleep.The pain typically gets better with activity or exercise.Back pain may begin in the sacroiliac joints (between the pelvis and the spine). Over time, it may involve all or part of the spine.You may lose motion or mobility in the lower spine. You may not be able to fully expand your chest because the joints between the ribs are involved.Fatigue is also a common symptom.Other, less common symptoms include:Eye inflammation or uveitisHeel painHip pain and stiffnessJoint pain and joint swelling in the shoulders, knees, and anklesLoss of appetiteSlight feverWeight lossSigns and testsTests may include:CBCESRHLA-B27 antigenX-rays of the spine and pelvisTreatmentYour doctor may prescribe nonsteroidal anti-inflammatory drugs (NSAIDs) to reduce inflammation and pain.Corticosteroid therapy or medications to suppress the immune system may also be prescribed. Drugs called TNF-inhibitors (etanercept, adalimumab, infliximab), which block an inflammatory protein, have been shown to improve the symptoms of ankylosing spondylitis.Some health care professionals use drugs that block cell growth (cytotoxic drugs) in people who do not respond well to corticosteroids or who are dependent on high doses of corticosteroids.Surgery may be done if pain or joint damage is severe.Exercises can help improve posture and breathing. Lying flat on the back at night can help maintain normal posture.Expectations (prognosis)The course of the disease is unpredictable. Symptoms may come and go at any time. Most people are able to function unless the hips are severely involved.ComplicationsRarely, people may have problems with the aortic heart valve (aortic insufficiency) and heart rhythm problems.Some patients may have pulmonary fibrosis or restrictive lung disease.Calling your health care providerCall your health care provider if:You have symptoms of ankylosing spondylitisYou have ankylosing spondylitis and develop new symptoms during treatmentPreventionPrevention is unknown. Awareness of risk factors may allow early detection and treatment.ReferencesGoldman L, Ausiello DA. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007.Sidiropoulos PI, Hatemi G, Song IH, et al. Evidence-based recommendations for the management of ankylosing spondylitis: systematic literature search of the 3E Initiative in Rheumatology involving a broad panel of experts and practising rheumatologists. Rheumatology (Oxford). 2008. 47(3):355-61.Dagfinrud H, Kvien TK, Hagen KB. Physiotherapy interventions for ankylosing spondylitis. Cochrane Database, Syst Rev. 2008. (1):CD002822.
There are many possible treatments available for spondylitis. Treatment is based on the kind of spondylitis, as there are different kinds. This includes medication, excercise and physical theraphy, postural practices, hot and cold theraphy and finally, surgery.
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Spondylitis has many symptoms. Some major symptoms of spondylitiis may include stiff necks, gradually worsening pain, headaches, balance loss, coughing, etc.
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