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How many males are currently living with hemohilia in the US?
It is estimated that about 20,000 males in the US are currently living with hemophilia. Hemophilia is a rare genetic blood disorder that primarily affects males. Treatment and management of hemophilia have significantly improved over the years.
Suppose this pedigree is for a disease called Huntington's disease. The allele for this disease is dominant. How many of the males shown in the pedigree can be expected to have or develop the disease?
four
At what age does hemophilia appear?
There is no clear date when the disorder first appeared. Since even today it takes some sophisticated blood tests in order to diagnose hemophilia the ability to unmistakably identify it did not exist until more recent years. As far back as the 2nd century AD however, there are references to what is believed to be hemophilia without the name "hemophilia" as we know it now. As it is customary for males of Jewish background to be circumcised, the first known reference believed to infer hemophilia comes in the form of an exemption for circumcision. Hemophilia has been written about many times since those days and it was even recognized that the disorder followed the female side of family lineage and largely affected males. The term "Hemophilia" was first used as a name for the disorder by a university in Zurich in 1878.
How many people get hemophilia a year?
You have to be born with hemophilia, it is not something people can "catch".
Is hemophilia a disorder?
The clinical answer would be yes, however there are many exceptions to the rule in the case of hemophilia. The trait for hemophilia is carried on the X chromosome and is often recessive. This being the case, since females have 2 X chromosomes, there is typically a dominant gene on their other X that corrects the disorder if one X carries the trait for hemophilia. Males, having only one X chromosome (paired with a Y chromosome) an only express the traits on the one X that they have. This being the case, a male with the trait for hemophilia on his X chromosome must be affected by it. In more recent years it has become understood that the trait for hemophilia is not as recessive as once thought. In many females the trait has shown incomplete or shared dominance with the otherwise normal gene. This often results in the female having low clotting factor levels and actually being considered a mild or moderate hemophiliac.
Can a blood transfusion cause hemophilia?
No. Hemophilia is a genetic disease. But many hemophiliacs can benefit from having them.
How males inherit hemophilia?
Hemophilia is passed down from mother to son. It is extremely rare for a woman to have hemophilia. It is necessary, though, for a woman to be a carrier of the disorder for her son to acquire this disorder. Females have two X chromosomes whereas males only have one. When a boy is born, he takes one X chromosome from his mother and one Y chromosome from his father. Therefore, he can only get hemophilia through his mother. Example One: Mother(Carrier)+Father(Non-Affected)=50% chance of their son acquiring the disorder and 50% chance of their daughter being a carrier. Example Two: Mother(Non-Affected)+Father(Hemophiliac)=All sons will be non-affected and all daughters will be carriers.
How many alleles for hemophilia do females have?
females have 2 alleles for hemophilia, (X^hX^H) and (X^hX^h) if H is the normal allele and h is the recessive allele for hemophilia
How many generation pedigree does the AKC offer?
4
Can boys carry hemophilia but not have it?
yes. One time six states had estimated how much of the population had hemophilia, and got about 7,000. There isn't a actual known amount of people that actually have Hemophilia, but it is estimated about 20,000 people in America that DO have it. You inheritet it from parents, also known as the term called "sex-linked". Hope i helped:)
Is hemophilia related to blood platelets?
No. There are several types of bleeding disorders. Hemophilia is a deficiency in clotting factor proteins VIII (Hemophilia A), IX (Hemophilia B), or XI (Hemophilia C). There are several other clotting factor proteins linked to coagulation, as well as the vonWillebrands protein, and platelet disorders. Hemophilia is simply the most widely recognized (by the general public) bleeding disorder. It is important to know that many other bleeding disorders exist, such as the platelet deficiency you are asking about.
Where can one buy Pedigree dolls?
There are many places online that one can buy Pedigree dolls. They can be purchased from websites such as Wonders of Youth, Gumtree and Diane's Dolls.
