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Hemophilia is passed down from mother to son. It is extremely
rare for a woman to have hemophilia. It is necessary, though, for
a woman to be a carrier of the disorder for her son to acquire this
disorder. Females have two X chromosomes whereas males only
have one. When a boy is born, he takes one X chromosome from
his mother and one Y chromosome from his father. Therefore, he
can only get hemophilia through his mother.
Example One:
Mother(Carrier)+Father(Non-Affected)=50% chance of their son
acquiring the disorder and 50% chance of their daughter being a
carrier.
Example Two:
Mother(Non-Affected)+Father(Hemophiliac)=All sons will be
non-affected and all daughters will be carriers.
Males get hemophilia from a carrier trait from their mother. Males can not get hemophilia from father. If father has hemophilia then sons do not have it and daughters are carriers. If mom is a carrier then 50-50 chance for sons to have it and 50-50 for daughters to be carriers. Males either have it or not they are not carriers. Females are carriers.
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Because this question specifies inheriting hemophilia, the above answer is mostly true. It is important to note that approximately 1/3 of the cases of hemophilia are believed to be the result of a random mutation and not inherited at all. Since the genetic sequences that code for hemophilia A & B are on the X chromosome the genetic transfer from parent to child controls the passage of these sequences.
A father provides his Y chromosome to his sons and his X chromosomes to his daughters. For this reason, only the daughter can inherit the trait from the father. The mother provides both sons and daughters with an X chromosome. This means that either son, or daughter, could inherit the trait from the mother.
I would like to point out that the term carrier is a highly debated subject, as many females also have clotting factor levels low enough to require treatment and be considered fully as hemophiliacs themselves.
Males with hemophilia definitely "carry" hemophilia. The tricky part is that a males will pass the mutation on to their daughters and will not pass the mutation on to their sons. Female carriers on the other hand have a 50% chance of passing the mutation on regardless if it's passed to a son or daughter.
Males are more apt to demonstrate hemophilia simply because the trait is located on the X chromosome. Females (which one can remember from science class) have two X chromosomes and no Y chromosomes. Males on the other hand have one X chromosome and one Y chromosome.
Each chromosome is like a set of instructions. When the body is making clotting factor proteins it reads the recipe exactly as instructed. If the recipe on one of the X chromosomes in a female is smudged or otherwise illegible (has the mutation) then the body can simply refer to the other X chromosome and get the correct information.
Since the male only has one X chromosome, they only have one set of instructions. If those instructions are illegible then there is no chance the factor protein will be made correctly.
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Are more likely to inherit hemophilia?
Males.
Do Male hemophiliacs inherit the disease from their?
Yes, males inherit hemophilia from their mothers who carry the gene on their X chromosome. Hemophilia is a genetic disorder that primarily affects males because they have only one X chromosome.
Does a human offspring inherit hemophilia from the mother or father?
Hemophilia is sex linked. Males inherit from their mother, daughters are carriers if the defective gene is inherited from one of either parent. A female must inherit two copies of the defective allele to have hemophilia .
Who can inherit hemophilia?
Anyone can inherit hemophilia. In most cases, it is a man whose mother is a carrier of the disease. It is extremely rare for a woman to have hemophilia but it is not uncommon for one to be a carrier. It is even possible for someone whose family has no record of hemophilia to get it through gene mutations.
Why Males having a greater chance of hemophilia?
Hemophilia occurs in the X chromosome, and males are the genders that have the X chromosome.
A woman is a carrier for hemophilia what is the chances for sons with hemophilia if the father does not have hemophilia?
If the mother is a carrier for hemophilia, there is a 50% chance that her sons will inherit the hemophilia gene, but only if the father does not have hemophilia. This is because sons inherit the X chromosome that carries the hemophilia gene from their mother. If the father does not have hemophilia, the son will not inherit a healthy X chromosome from him to compensate for the defective X chromosome from the mother.
Hemophilia results from an allele then is?
Recessive?? (i.e., you would need to inherit one from each parent to have hemophilia)
Is albinism hemophilia progeria or huntingtons disease more common in males?
Hemophilia
Can a male be a carrier for hemophilia?
Yes, males can be carriers for hemophilia. While hemophilia is more common in males, as it is an X-linked genetic disorder, females can also carry the gene and pass it on to their children. Males who inherit the gene will have hemophilia, while females who inherit the gene can be carriers and potentially pass it on to their children.
How many males are currently living with hemohilia in the US?
It is estimated that about 20,000 males in the US are currently living with hemophilia. Hemophilia is a rare genetic blood disorder that primarily affects males. Treatment and management of hemophilia have significantly improved over the years.
What is the rate of occurrence for kids to have hemophilia?
Approximately 1 in 5000 males born have hemophilia. Approximately 1 in 10,000 children have hemophilia.
Which of the parents can pass the allele for hemophilia to a daughter?
The father is the one who can pass the allele for hemophilia to a daughter. Hemophilia is a recessive X-linked disorder, so the daughter would need to inherit the hemophilia allele from her father.
