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In Myelodysplastic Syndromes (or Diseases) the bone marrow fails to produce enough blood cells: red blood cells, white blood cells, and platelets. Patients are usually elderly, who went through chemotherapy or radiotherapy at some earlier time for another malignancy. Depending on the percentage of blast cells (immature precursor cells = cells the bone marrow released into the blood before it "matured") the diseases classified as low grade (less than 5% blast cells) or High risk (more then 5% blast cells).

Central Diabetes insipidus (associated with decreased production/release of anti-diuretic hormone into the blood), is different from Diabetes Mellitus (lack/resistance to insulin hormone).

On rare occasions, if the leukaemia cells infiltrate the Hypothalamus, severely enough to affects its anti-diuretic hormone balance, Central Diabetes Insipidus becomes a complication of Myelodysplastic Syndrome.

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Q: How is diabetes and myelodysplasia connected?
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