Calamine lotion doesn't actually treat the chickenpox virus. It does, however, help relieve the itching that is associated with the spots. It contains an anti-itching agent to relieve itching.
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Shingles and cold sores are not the same thing. Shingles are caused by the chicken pox virus, while cold sores are caused by oral herpes. You can try callomine lotion to help with the itching and maybe try some pain killers to help with the pain.