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Inflammation is a response from your immune system in response to an irritant. For example, if you sprain your ankle, your immune system creates a protein called a Circulating Immune Complex (CIC for short). The CIC travels down to the injured ankle and causes pain and swelling.

The pain you feel is to inform you of the injury or damage. And the swelling is protective as it prevents you from moving it and causing more irritation. This is also your body's way of running to the problem with fresh blood, antibodies and vital cells in order to begin healing and repairing the damage.

from: http://www.losethebackpain.com/inflammation5.html

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Q: Does swelling hurt
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