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No is the simple answer. Cholesterol is for the most part evenly distributed in the blood and therefore when donating blood you take cholesterol with the blood. Your body will have a lower MASS of cholesterol but the CONCENTRATION of cholesterol has not changed, which is what is important for you I presume.

However, when giving blood they encourage no fatty meals or food 24 hours before to avoid high levels of fats and cholesterol in the blood, which means you shouldn't e giving blood if you have high cholesterol.

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Q: Does giving blood lower cholesterol
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