Idiopathic myelofibrosis typically becomes progressively worse and can cause death
Myelofibrosis goes by many names including idiopathic myelofibrosis, agnogenic myeloid metaplasia, chronic myelosclerosis, aleukemic megakaryocytic myelosis, and leukoerythroblastosis
About one quarter of all patients with myelofibrosis have no symptoms (asymptomatic)
Myelofibrosis is caused by an abnormality in a single stem cell, which causes it to grow out of control
Because symptoms are similar to other diseases (mostly leukemias), myelofibrosis is not easy to diagnose
Although historically there has not been much improvement in the treatment of myelofibrosis, that has changed recently. The main treatment now consists of taking a medication known as "Jakafi" which targets the gene thought to cause myelofibrosis.
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