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Gliomas are not frequently hereditary, although a small percentage of patients do see a familial pattern. Early studies have shown that up to 10% of glioma patients have a 1st degree relative also diagnosed with the disease. Individuals with a family history of specific cancers other than glioma may have an increased glioma risk as well. One of the earliest studies of hereditary glioma rates was conducted by several prominent neuro surgeons and published in 2003:
Cancer in First-Degree Relatives and Risk of Glioma in Adults
http://cebp.aacrjournals.org/content/12/12/1443.full
In 2009, researchers at UCSF discovered an actual inherited link in familial gliomas, which may exist in as many as 20% of cases. UCSF genetic epidemiologists Margaret Wrensch, PhD, Jeffrey Chang, MD, PhD, and John Wiencke, PhD published their work in the July 5, 2009 online edition of the scientific journal Nature Genetics.
Brain Cancer Linked to Inherited Genetic Risk
http://www.ucsf.edu/news/2009/07/8190/genetic-risk-brain-cancer-glioma-called-glioblastoma
In 2007, researcher Melissa Bondy, PhD of the MD Anderson Cancer Center in Houston, introduced the GLIOGENE Project as an international, multi-institutional, five-year study to determine genetic risk factors to help predict brain tumors in families of glioma patients. Results from this study should be available after 2012. For more information on GLIOGENE, see:
http://www.mdanderson.org/publications/cancerwise/archives/2007-january/cancerwise-january-2007-worldwide-study-looks-at-inherited-brain-tumors.html
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What is the most fatal brain disease?
Severe trauma is the most likely to be immediately fatal. However, any condition that affects the brain can cause death.
What are Grade IV astrocytomas also called?
Grade IV astrocytomas are also called glioblastoma multiforme (GBM) tumors.
What part of the body does glioblastoma multiform affect?
Glioblastoma multiforme (GBM) affects the brain and spinal cord. It is a type of aggressive brain cancer that arises from glial cells in the brain, particularly astrocytes. GBM is characterized by its fast-growing and invasive nature, making it difficult to treat.
What are Primary brain tumors?
The most common primary brain tumors include gliomas such as astrocytomas, ependymomas, and oligodendrogliomas
Do Malignant brain tumors have borders?
Malignant brain tumors do not have distinct borders
Is metastatic SOL's in brain is same as brain cancer?
Metastatic SOL's or tumors found in the brain are same as brain cancer. Metastatic tumors are one of the most common type of tumors found in the brain.
What are the prevalent primary brain tumors?
Gliomas are the most prevalent primary brain tumors
What is inside Benign brain tumors?
Benign brain tumors are composed of harmless cells
Who can glioblastoma effect?
Glioblastoma (GBM) can effect everyone around you. It is a very aggressive type of brain cancer.
Who is at a higher risk of brain tumors?
Men and caucasians have a higher risk of developing brain tumors
Are metastatic brain tumors deadly?
yes, metastatic brain tumors can be deadly if not treated properly.
What is the tumor of the brain?
A brain tumor is a group, or mass, of atypical cells to your brain. Your skull, which encloses your mind, is very inflexible. Any growth internal this type of limited area can purpose problems. Brain tumors may be cancerous (malignant) or noncancerous (benign).
