Mastipation is not a recognized medical term. It may be a misspelling or typo. If you meant to ask about constipation, it can be caused by factors like a low-fiber diet, dehydration, lack of physical activity, or certain medications. It's important to stay hydrated, eat a healthy diet with plenty of fiber, and exercise regularly to prevent constipation. If you are experiencing persistent constipation, it's best to consult a healthcare provider for proper evaluation and management.