An atom.
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an atom Actually, the smallest unit of matter is called a Quark. Quarks combine to form protons and neutrons, which are the core of an atom.
the basic structural unit of living matter is THE ATOM
When you consider the composition of living and non living things, both can be broken down into what comprises them. If one considers non-living matter, then "particle" may be used to describe the smallest unit. As knowledge advances, a "particle" by definition has evolved i.e., quarks being the smallest "particle" of an atom whereas for years it was thought that the atom was the smallest unit of matter. Conversely, the cell is considered the smallest unit of organic (living) matter The only major difference between them is that a cell is the smallest particle of a living object and a molecule (made up of atoms) is the smallest unit of a nonliving object.
In digital imaging, a pixel is a single point in a raster image, or the smallest addressable screen element in a display device; it is the smallest unit of picture that can be represented or controlled
That would be an atom. Atoms go down to protons, neutrons and electrons, but these do not have unique characteristics. So, the smallest particle with unique characteristics is an atom.