Knowledge is any discrete or abstract concepts of natural or supernatural phenomena assimilated & recorded as thoughts by the human cognitive neural cortices matrix domain.
Another view:
Knowledge is any acquired experience that helps the knower to make sense of the world.
It's when you know something and you are educated.
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Science is a system of knowledge and the methods used to find that knowledge.
All science is knowledge but not all knowledge is science.
Not book knowledge. Knowledge acquired by experimenting or testing by yourself.
In an evolutionary sence knowledge and the thirst for knowledge is for the purpose of adaption. As we appear to be in a multiple reality (infinity on infinity) the rationalisation of knowledge would seem to be paramount.
we do we gain for knowledge? What we gain from knowledge is facts.