a. The substrate can be altered so it is induced to fit into the enzyme's active site. b. The enzyme changes its shape slightly as it binds to the substrate. c. The enzyme is altered so it is induced to fit many different types of substrate.
d. Several sites on an enzyme can be induced to act on a substrate.
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According to lock and key model both the enzymes and the substrate possess specific geometrical shapes that fit exactly into one another. WHILE According to the induced fit model enzymes are more flexible structures and their active site is reshaped as substrate interacts with the enzymes.
Scientific theories can be disproved. This is a key part of the scientific method, creating hypothesis that can be disproved if they are incorrect. However, you can never really prove a hypothesis - you can find evidence that either fits or doesn't fit. If it doesn't fit the hypothesis needs to be revised or thrown out. If the evidence supports the hypothesis, there may be something that you are missing which may reject the hypothesis.
Does it fit all the known facts AND can it be tested against reality.
The induced fit model is the theory that instead of enzymes and substrates fitting exactly together, as in the lock and key model, the enzyme changes shape around the substrate to bind with it. Non-competitive inhibition is where the inhibitor does not fit into the active site, but into another site on the enzyme instead, which changes the shape of the active site.
The experiment must be redone and checked for potential errors; does the conclusion of the experiment continuously disprove the hypothesis, the latter must be changed to fit.