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It depends on what elements constitute the crystal. Some crystals can be toxic, others are harmless. It also depends on the type of contact you come into with it. A crystal such as table salt, for example (Soduim Chloride) is considered harmless, and even improves the taste of some foods, yet if it is consumed in great quantities it can become deady. Not because it is toxic, but because your body cannot deal with large amounts of it. If a crystal contains elements that are, in their natural state, toxic; then yes, the crystal itself would also likely be toxic.
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