Completely depends on the beer. You say ale, which only means the yeast ferments on the bottom for a shorter period of time than a lager, and includes the following styles: blondes, hefeweizens, ambers, pale ales, IPA's, porters, stouts, Belgian ales... and hundreds more. (Lagers are Pilsners, doppelbocks, etc.) Some blonde beers have around 150-200 calories. Sierra Nevada Bigfoot Barleywine-style Ale has 350+ calories per 12 oz. bottle. Best way to find out is to research the particular beer you prefer to drink.
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142 Calories in a pint of Guiness
Is this an American pint or an empirical pint?
it depends what kind of Guinness beer you want to know about, there's different kinds.